comparing live lecture, internet-based & computer-based in-struction: a randomized controlled trial

background :comparing computer and internet based instruction with traditional giving lecture would provide enough evidence to identify best teaching practice. in this study, we compared lecture, interactive internet based and computer based learning regarding medical students' knowledge acquisition and satisfaction in teaching pathophysiology of hematology and oncology.   methods : eighty four medical students were randomized into three groups and an identical faculty member conducted the instructions through the above mentioned methods. students' knowledge was assessed one week before and immediately after the interventions by pre and posttest. students' satisfaction was assessed using a validated 5-point likert scale.   results : the results showed that students' satisfaction was significantly higher in interactive internet based group than other ones (p=0.05). there were a significant increase between pre and posttest scores in all groups (p=0.000). we used ancova to compare score changes in the study groups, with posttest scores as the dependent factor and pretest scores as covariate and knowledge acquisition was significantly higher in interactive internet based group than other two groups (p=0.026).   conclusion : the study showed that although interactive internet based instruction is a difficult and time consuming method, it is recommended to integrate this method to medical curricula.